hollow fiber module production

Membrane filters & modules

Our heart beats for membrane technology!
Choosing the right membrane and the right module for your desired project is the key to success.
We will find the best solution with you!

Competence & experience

Alpha Plan has more than 25 years of experience in filter manufacturing - from the development and production of individual prototypes, to the manufacture of millions of hollow fiber modules per year, to the delivery of a fully automated production line.

Standard hollow fiber filter

Do you have a specific application in mind and want to test the approach quickly with a standard module? Would you like to start with your idea and test the basic concept?

Sometimes a standard hollow fiber filter is sufficient.
And if you need certain adaptations later on, we will be happy to do this for you. A selection of our standard membrane filters, which we have permanently in stock, can be found here:

Ultrafiltration hollow fiber modules >
Endotoxin and water filter modules >
Gas transfer modules >
New! You can now also purchase our high-quality microfilters, ultrafiltration filters and gas transfer filters around the clock in our new online store. 
hollow fiber module manufacture technology
hollow fiber module production

Customized membrane filters

Do you need a special membrane filter module that you cannot find here? Do you need a special module size, different connections or a different type of membrane? 

Talk to us, we will find a customized solution for you.

Contract development and production of membrane-based filters

Do you need a specific filter module for a specific application? Would you like to manufacture an entire cassette system including a membrane module? Do you need series production of over 100,000 modules? Are you perhaps thinking about setting up your own production line to ensure a constant supply?

Then Alpha Plan is the right place for you! Our competent project team of engineers from the fields of medical technology, biotechnology, physical engineering and quality management will develop the ideal product for you, taking series production into account.

All our filter modules are developed and manufactured in-house, making them a genuine Made in Germany product. Alpha Plan has production lines under clean room conditions at its disposal for this purpose. The hollow fiber membranes used are sourced from renowned German and Japanese membrane suppliers in order to offer you a wide selection of modules.

Visual inspection of hollow fiber filter membrane end faces

Depending on the number of modules required, we can respond very flexibly to your requirements, even if you only need a few prototypes or small batches. A decision for a manual, semi-automated or fully automated production process makes this possible.

Production takes place in a clean room under controlled manufacturing conditions, in accordance with the ISO-14644-1 Class 8 standard in the central production area and ISO-14644-1 Class 6 at the laminar flow workstation.

High quality and standardized quality assurance are the basis of our actions. Our production team is highly competent and pays attention to every detail. This is confirmed by our certified quality management system ISO 9001: 2015 and EN ISO 13485: 2016, as well as our excellent customer satisfaction.

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Filter development and production

In Radeberg, we develop and manufacture microfiltration, ultrafiltration and gas transfer filters under cleanroom conditions for various applications in the medical, biotechnology, life sciences and pharmaceutical industries.

Alpha Plan produces its own standard filters and also customized filters on customer request.

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Endotoxin and water filter modules

Application examples:

  • Endotoxin and pyrogen separation
  • Water treatment
  • Reverse osmosis water
Art. No. Product Dimensions (Ø/length) w/o connections Membrane MWCO Connections Filter range Max. Pressure Filtration capacity (initial flow capacity) (+/- 15%, 298 K)
0510117 Endotoxin filter EF-PSH-15 41 / 260 mm Polysulfones 20 kDa  Hose Barb 6.0 mm 1.4 m² 3 Bar 240 l/h
0510118 Endotoxin filter EF-PSL-15 41 / 260 mm Polysulfones 5 kDa Hose Barb 6.0 mm 1.4 m² 3 Bar 15 l/h
0510129 Water filter UF-PSH-15 41 / 260 mm Polysulfones 20 kDa Tube fitting OD 8.0mm 1.4 m² 3 Bar 240 l/h

MWCO - Molecular Weight Cut-Off; ICS - Intra Capillary Space; ECS - Extra Capillary Space; TMP - Trans-membrane pressure, FLC - Female Luer Connector; Ø - Housing diameter; Length - Housing length without end caps and connections

Ultrafiltration hollow fiber modules

Application examples:

  • Upstream cell and protein concentration
  • Downstream bioprocessing, protein and antibody purification
  • Perfusion filter for stirred tank or wave bioreactors
  • Media and buffer filtration
  • Virus filter
Art. No. Product Dimensions (Ø/length) w/o connections Membrane MWCO Connections ICS area ECS area Inner volume Outer volume
0510038 Ultra S - 20 kDa 12 / 60 mm Polysulfones 20 kDa FLC 130 cm² 180 cm² 0.9 ml 1.6 ml
0510100 Ultra S - 5 kDa Polysulfones 5 kDa
0510114 Ultra M - 20 kDa 12 / 150 mm Polysulfones 20 kDa FLC 380 cm² 530 cm² 2.2 ml 4.7 ml
0510102 Ultra M - 5 kDa Polysulfones 5 kDa
0510103 Ultra L - 20 kDa 21 / 120 mm Polysulfones 20 kDa FLC 1800 cm² 2500 cm² 10.5 ml 17.5 ml
0510104 Ultra L - 5 kDa Polysulfones 5 kDa
0510113 Ultra XL - 20 kDa 46 / 260 mm Polysulfones 20 kDa Hose Barb 6.0 mm 1.8 m² 2.6 m² 100 ml 220 ml
0510116 Ultra XL - 5 kDa Polysulfones 5 kDa

MWCO - Molecular Weight Cut-Off; ICS - Intra Capillary Space; ECS - Extra Capillary Space; TMP - Trans-membrane pressure, FLC - Female Luer Connector; Ø - Housing diameter; Length - Housing length without end caps and connections

Gas transfer modules

Application examples:
  • Oxygen enrichment / carbonation of liquids
  • Degassing of liquids
  • Bioreactor oxygenators
Art. No. Product Dimensions (Ø/length) w/o connections Membrane Connections Inner surface Outer surface Intracapillary volume Extracapillary volume
0510142 GTM S 12 / 60 mm PMP FLC 80 cm² 160 cm² 0.6 ml 1.3 ml
0510143 GTM M 21 / 120 mm PMP FLC 0.10 m² 0.19 m² 6 ml 17 ml
0510144 GTM L 26 / 120 mm PMP FLC 0.15 m² 0.29 m² 9 ml 26 ml
MWCO - Molecular Weight Cut-Off; ICS - Intra Capillary Space; ECS - Extra Capillary Space; TMP - Trans-membrane pressure, FLC - Female Luer Connector; Ø - Housing diameter; Length - Housing length without end caps and connections